There is a debut for Jess Pegram who joined on loan from Brighton earlier this week, alongside a first start of the campaign for Kim Shin Ji and Kathy Hill.
It means Jenna Fife retains her place between the posts, behind a backline of Jodi McLeary, Pegram, Hill and captain Nicola Docherty.
In midfield, Alice Griffiths partners Shin Ji, with Mia McAulay operating in a more advanced role.
Katie Wilkinson leads the line in attack, supported on either flank by Brogan Hay and Lizzie Arnot.
Among the substitutes for Rangers in Hamilton is Telma Ivarsdottir, Eilidh Austin, Laura Berry, Camille Lafaix, May Cruft and Fallon Connolly-Jackson.
Please note the 3:05pm kick-off and you can enjoy the match live on Sky Sports.
RANGERS: Fife, McLeary, Pegram, Hill, Docherty, Griffiths, Shin Ji, McAulay, Hay, Arnot, Wilkinson
SUBS: Ivarsdottir, Austin, Berry, Lafaix, Cruft, Connolly-Jackson
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