The Light Blues marched into the next round of the competition with a 3-1 win over Bo’ness United last month and they will be keen to extend their run in the cup against strong League Two opposition.
Mason Munn returns between the posts, behind a backline of Adam Devine, Leon King who captains the side, Clinton Nsiala, and Zander Hutton.
In midfield, Bailey Rice is once again partnered by Paul Nsio who was on the scoresheet in the previous round, with Calum Adamson, who celebrated his 17th birthday last week, operating in an advanced position.
16-year-old Josh Gentles leads the line, where he is supplemented on the flanks by Alex Lowry and Findlay Curtis.
On the bench for the young Gers this evening is Alfie Halliwell, Greig Allen, Kristian Webster, Connor Allan, Blaine McClure, Callum Burnside, Kerr Robertson and Chris Eadie, while there is a return to the matchday squad for Zak Lovelace.
Kick-off in Hamilton is 7:45pm and you can stay up to date with the action on X @RFC_Youth.
RANGERS B: Munn, Devine, King, Nsiala, Hutton, Rice, Nsio, Adamson, Curtis, Lowry, Gentles
SUBS: Halliwell, Allen, Webster, Allan, McClure, Burnside, Robertson, Lovelace, Eadie