Among those introduced to the starting lineup is 16-year-old May Cruft, who replaces Alice Griffiths, and captain Nicola Docherty, coming into the defence in place of Fallon Connolly-Jackson.
Leah Eddie, who enjoyed a stellar debut campaign at the Gers last season, also features in the matchday squad for the first time this campaign following her return from a lengthy injury lay-off.
It means Jenna Fife retains her place between the posts, behind a backline of Eilidh Austin, Jess Pegram, Kathy Hill and Nicola Docherty.
In midfield, Jodi McLeary partners Cruft, while Kim Shin Ji will be keen to continue her excellent start to the season in an advanced role.
Katie Wilkinson leads the line in attack, supported on either flank by Mia McAulay and Lizzie Arnot.
Among the substitutes in Govan is Telma Ivarsdottir, Megan Cunningham, Eddie, Quinty Sabajo, Laura Berry, Griffiths and Connolly-Jackson.
Kick-off at Ibrox is 4:10pm and supporters can enjoy the match live on BBC Alba.
RANGERS: Fife, Austin, Pegram, Hill, Docherty, McLeary, Cruft, Shin Ji, McAulay, Arnot, Wilkinson
SUBS: Ivarsdottir, Cunningham, Eddie, Sabajo, Berry, Griffiths, Connolly-Jackson
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