The Gers are seeking to overturn a 2-0 first-leg deficit, and from the side which recorded a memorable Old Firm triumph at the weekend, in comes Kirsty Smith, Eilidh Austin, Fallon Connolly-Jackson and Hannah Blake.
It means Jenna Fife retains her place between the posts, behind a backline of Smith, Austin, Mijke Roelfsema, Nicola Docherty and Connolly-Jackson.
In midfield, Blake is restored to the side following her goal against Celtic on Sunday, where she is joined by Jodi McLeary and May Cruft.
Laura Berry leads the line in attack, and she is supplemented by Calliste Brookshire.
Among the substitutes in Cumbernauld is Lola Rarity, Bailley Collins, Lily Boyce, Kathy Hill, Isla Miller, Sophie Black, Gry Boe Thrysoe, Brogan Hay, Eva Hendle and Katie Wilkinson.
Kick-off is 7pm and the match is live on the official Rangers YouTube channel.
RANGERS: Fife, Smith, Austin, Roelfsema, Docherty, Connolly-Jackson, Blake, Cruft, McLeary, Brookshire, Berry
SUBS: Rarity, Collins, Boyce, Hill, Miller, Black, Thrysoe, Hay, Hendle, Wilkinson