The young Gers moved onto six points with their midweek success away to League Two leaders Clyde, and from the side which overcame the Lanarkshire outfit, in comes goalkeeper Greig Thackray and Calum Young.
It means Thackray replaces Sam Reid between the posts, behind a backline of Young, Arran Kerr, Conor Owen and Jack Wyllie.
In midfield, 16-year-old Luca Rankin is given the nod alongside Ben Hutton.
Josh Gentles, who celebrates his 19th birthday today, leads the line in attack, where he is supported by Zebedee Lawson, Ashton Patton and captain Zander Hutton.
Among the substitutes in Dumfries is Jaden Millarvie, Jack Caldwell, Luke Ramage, James Reid, Lyle Wark, Ethan Molloy, Cameron Fernie, Jackson Barr and Daniel Owoyomi.
Kick-off is 8pm and the match is live on Premier Sports.
RANGERS: Thackray, Young, Kerr, Owen, Wyllie, Z. Hutton, Rankin, B. Hutton, Lawson, Patton, Gentles
SUBS: Millarvie, Caldwell, Ramage, Reid, Wark, Molloy, Fernie, Barr, Owoyomi
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